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Digital newsletter of IDIBELL
Number 144 - 19 April 2016

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Improved Biomarkers and Clinical Outcome Measures Program (Pre-proposal)- MJFF
Identifier: 137/16
Categorie: Projectes de recerca
Financing entity: 386
OTRI deadline: 11/05/2016
Call aim:

To  support development of biomarker and outcome measures to garner knowledge that is critically important to the Parkinson´s Disease field – from a drug’s mechanism of action and its relevance to disease biology to understanding the biological basis underlying patient heterogeneity in drug response. In addition to general biomarkers of the disease and clinical features, MJFF is also interested in biomarkers of high-priority targets such as alpha-synuclein, LRRK2, parkin and glucocerebrosidase. The following types of biomarker and outcome measures and assays are encouraged:

  • Imaging studies
  • Clinical/physiological studies
  • Biochemical assays/ outcome measures
  • Data Science

 The following types of biomarker studies are not encouraged under this initiative:

  • Unbiased discovery efforts
  • Proposals that do not contain any preliminary data in human subjects or tissue (novel tracer development projects are a potential exception to this rule)
  • Projects that could not be implemented into clinical trials in the next several years
Duration: <p>1-3 years</p>
  • Applications may be submitted by: U.S. and non-U.S. entities, public and private non-profit entities, such as universities, colleges, hospitals, laboratories, units of state and local governments, and eligible agencies of the federal government.
  • Post-doctoral fellows are NOT eligible to apply as principal investigators to this program.
  • Applicants should NOT submit the same idea to multiple programs of MJFF.

Applications will only be accepted through the online submission system, completing the following information:

  • Principal Investigator (PI)
  • CoPI and/or Collaborator(s) (if any)
  • Project Duration
  • Project Budget
  • Project Abstract (300 word limit) – Brief summary of the goals of your project
  • Pre-Proposal Template (max 2 pages)
More information:

Applicants are proposed time-dependent milestones to ensure completion of study objectives. Continuation of funding will be dependent upon successful completion of these milestones.

Only those pre-proposals deemed to be of suitable scientific merit will be invited to submit a full application (deadline: August 5th, 2016). If invited to submit a full proposal, applicants will receive additional instructions and information necessary for submitting online.


General review criteria:

  • Responsiveness: Projects should fit the goals of the particular funding program
  • Scientific rationale for the proposed study and its impact for patients
  • Innovation
  • Overall experimental design and objectives
  • Investigator/Environment: The investigative team should be appropriately trained and well suited to carrying out the proposed work
  • Sharing Plan: Applicants should provide details on how data and/or research tools (e.g., clinical datasets, research reagents and models) will be made available to the public for future research purposes
  • Budget: The proposed budget should be reasonable and justified for the research proposed. Project Timeline: Timelines for completing each study should be clearly defined and include relevant milestones. Project goals must be achievable within the award period
  • MJFF Portfolio: Overlap with other MJFF investments are considered before making any final funding decisions
  • Grantsmanship: Ideal proposals are written clearly and logically, with sufficient details to ensure that reviewers understand all critical aspects of the proposed project methods and plan
Place of presentation:
Cofinancing by the institution: No
Specialist manager:
Date of expression of interest: 04/05/2016
OTRI deadline: 11/05/2016
Call deadline: 18/05/2016
Resolution date:
Budget advices (URL):
Calls (URL): Administratine Guidelines Fellowship on-line submission system
Other documents: Guidelines    Pre-proposal Instructions and Template    Guidelines    Pre-proposal Instructions and template    Guidelines    Pre-proposal Instructions and template   

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